Anastasios Manessis, Founder and Medical Director, Endocrinologist at neXendo Wellness

Anastasios Manessis, MD, FACE, ECNU, ABOM

Founder and Medical Director, Endocrinologist

Sees clients in: Manhattan · Long Island City

Board-certified in Endocrinology, Diabetes and Metabolism · Board-certified in Obesity Medicine · MD, SUNY Buffalo

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About Dr. Manessis

neXendo Wellness started with something Dr. Manessis kept seeing in his endocrinology practice. A prescription alone was never the whole answer. Hormones, medication, food, movement and daily habits all pull on each other, and treating one while ignoring the rest is how people end up stuck. He built neXendo to fix that: one team, working from one set of data.

He is double board-certified, in Endocrinology, Diabetes and Metabolism and in Obesity Medicine. He is a Fellow of the American College of Endocrinology and holds the ECNU certification in endocrine neck ultrasound. His training ran through New York. Undergraduate at Manhattan College, magna cum laude with distinction in biochemistry. Medical degree from the State University of New York at Buffalo. Then a combined residency in internal medicine and pediatrics at New York Medical College at Saint Vincent's Hospital, a year as chief medical resident, and a two-year clinical fellowship in endocrinology, diabetes and metabolism, where part of his research looked at insulin pumps for people with type 2 diabetes.

He taught in the Department of Medicine at New York Medical College from 2008 to 2010 and joined the faculty at New York University in 2011. He has also spent years on clinical research, including long-term studies on the safety and effectiveness of GLP-1 agonists and other weight loss medications. That background shapes how he practices. When a patient asks whether a medication makes sense for them, he is answering from studies he helped run.

At neXendo, patients see him for weight management, type 2 diabetes, thyroid and hormone conditions, osteoporosis and metabolic health. Insulin pump therapy for diabetes remains a particular interest of his. Every plan starts with testing. Metabolic rate, body composition, bone density and lab work are reviewed before any recommendation is made, and the registered dietitians and medical fitness trainers he works with build their side of the plan from those same results.

Where Dr. Manessis can help

Ready to start with the data?

A first visit with Dr. Manessis begins with testing and a full review of your history, so the plan that follows is built for you rather than for an average.

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Or call: Long Island City 718-704-5376 · Manhattan 212-675-9332.

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