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Comprehensive wellness,
on your body’s terms

Nutrition, Exercise, Endocrinology all under one roof in New York City collaborating on your plan towards improved health and wellbeing.

  • Founded by Dr. Anastasios Manessis: double board-certified endocrinologist

We start with data, then work together to craft a plan
fully personalized to your body’s needs

Your baselineSample report
Resting metabolic rate
1,847kcal/day
Body fat
24.3%
Muscle mass
68.4lb
Vitamin D
32ng/mL
DEXA ScanBone density + body comp
Lab workHormones + metabolism

Women's Wellness * Pre-Diabetes * Insomnia * Type 1 Diabetes * Hashimoto's * Type 2 Diabetes * Gestational Diabetes * Thyroid Balance * Osteoporosis * Osteopenia *Hyperthyroidism * Hypothyroidism * Weight Loss * GLP-1 Support * Sleep Optimization * PCOS/PMOS * Sports Optimization * Longevity * Menopause * Perimenopause * Bone Health * General Health * Obesity *

Women's Wellness * Pre-Diabetes * Insomnia * Type 1 Diabetes * Hashimoto's * Type 2 Diabetes * Gestational Diabetes * Thyroid Balance * Osteoporosis * Osteopenia *Hyperthyroidism * Hypothyroidism * Weight Loss * GLP-1 Support * Sleep Optimization * PCOS/PMOS * Sports Optimization * Longevity * Menopause * Perimenopause * Bone Health * General Health * Obesity *

As featured on
Targeted analysis

What we measure before anything gets planned

Fully holistic. Fully personalized.

Every plan here starts with targeted analysis. Body composition, bone density, lab work, and resting metabolic rate give your care team a clear read on where your health stands. Your wellness plan is built from those results, then adjusted as your numbers change.

Shop all wellness plans + testing

Did you know that you can actually rebuild bone density?

Bone is living tissue, and loading it is what tells it to hold on to density. ONERO® is a resistance and impact program built around that, offered at neXendo Wellness for people managing low bone density. We run it inside the practice, so whoever writes your progression can see your scan and your labs instead of guessing. Every session is supervised.

See how ONERO works

Nutrition

Exercise

Endocrinology

neXendo is named for the three things we specialize in combining. Most people get sent to those three separately and end up managing the handoffs themselves, carrying their own results between offices that never compare notes.

We put all three in one place and give them one set of your data to work from

Listen Up

Come learn with us!

Listen to our monthly podcast, tune in on social media for weekly insights from our nutrition and fitness teams, and read a backlog of helpful deep-dives on our blog.

Abigail lost more than 80 pounds. Her A1C came down with it.

“This program did not just help me work out. It helped me change my life.”

Abigail, neXendo patient

Abigail came to us after a diabetes diagnosis in 2023.

Read Abigail’s story